Join us for the GW Biomedical Cross-disciplinary Seminar Series: Connecting Academic Research & Inquiry Across Disciplines (CDSS). This virtual lecture series explores a new cross-disciplinary topic each year. The goal is to promote networking and collaboration in translational health among researchers, health care providers, and policy makers from different disciplines to shift the paradigm—from seeking a cure to developing a strategy of prevention.
2023-24 — CELLULAR METABOLITES
To maintain routine daily operations, cells must tightly regulate biochemical reactions that produce or consume energy as they respond to environmental changes. These collective reactions are more simply referred to as “cellular metabolism” and the substances produced during metabolism are known as metabolites. Cells produce different types and quantities of metabolites based on the available fuel source and signaling from the environment. In addition to providing energy, metabolites can function as powerful signaling molecules or modulate the function of proteins. Dysfunction within metabolic processes or the downstream function of metabolites is central to many pathological conditions. Therefore, there is a strong need to develop new experimental approaches and computational tools to investigate how cellular metabolism and its metabolites contribute to pathophysiology. As new discoveries explain how metabolites participate in various disease settings, new translational approaches and clinical treatments are being developed to target cellular metabolism and metabolites.
Given their critical contribution to regulating cellular function, cellular metabolites have become a hot topic in biomedical research. The 2023-24 CDSS will cover the science of cellular metabolites to foster cross-disciplinary communication and ideas from the perspectives of basic science, translational science, and clinical care.
The series runs from September 2023 to May 2024. These virtual events are open to all and will cover the following topics:
- Interactions Between Immunity and Metabolism
- Development of Single Cell Technologies for Metabolomics
- Metabolites as Biomarkers
- Computational Approaches to Investigate Metabolism
- Metabolites in Disease
Seminars
| Decoding Metabolomics Data to Infer Biological Insights Wednesday, November 15, 2023 (12:00 p.m. – 1:00 p.m. ET) |
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| Speaker: Ali Rahnavard, PhD, Assistant Professor of Biostatistics and Bioinformatics, GW Milken Institute School of Public Health |
| Interaction between Immunity and Metabolism in Disease: Lessons Learned from Acute Infection Friday, September 29, 2023 (12:00 p.m. – 1:00 p.m. ET) |
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| Speaker: Ioannis Koutroulis, MD, PhD, MBA, associate professor of Pediatrics, Emergency Medicine, Genomics and Precision Medicine and associate dean of MD Admissions at the GW School of Medicine and Health Sciences. | |
| Watch Video | |
Previous Seminars
GW Biomedical Cross-disciplinary Seminar Series (Video Playlist)
The series was organized by the GW School of Medicine and Health Sciences’ (SMHS) Office of Integrative Medicine and Health and the Department of Biochemistry & Molecular Medicine. The seminar series is supported by departmental funding and the generosity of Ellen J. LaBelle, MD `74, RESD '78, associate clinical professor of the Department of Psychiatry and Behavioral Sciences, and John Pan, MD '70, RESD '74, clinical professor, Department of Clinical Research and Leadership and founding medical director, Office of Integrative Medicine and Health.
For more information, contact co-organizers Leigh Frame, PhD, MHS, CERT ’20, associate professor, Department of Clinical Research and Leadership, Director, Integrative Medicine Programs, and Executive Director, Office of Integrative Medicine and Health, at leighframe@gwu.edu or 202-994-0184, and Brett Shook, PhD, assistant professor, Department of Biochemistry & Molecular Medicine, brettshook@gwu.edu or
202-994-1285.