Preparing and submitting (and re-submitting) an NIH biomedical research grant application to support your research is arduous. The Office of Extramural Research provides a general R01 overview that involves communications with grants support and sponsored projects and NIH staff.
An R01/R21 checklist developed at MIT highlights application sections with Forms E. This is for information only, always check for the most current instructions in the funding announcement.
NIH Information useful to Write Your Application.
For any grant, a key section is the Specific Aims.
Update your NIH Biosketch
Use your professional CV to create and update your NIH Biosketch. See NIH Biosketch Format pages, instructions, and samples for fellowship and non-fellowship style biosketches. Always be sure to use the most recent forms.