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Research investigates the interactions between HIV and cholesterol, including the effects of HIV protein Nef on cholesterol homeostasis and the mechanisms behind the effects of genes regulating cholesterol metabolism on HIV replication, latency and pathogenesis. Research also includes analysis of…
Research focuses on the epigenetic changes in cancer and how epigenetic drugs can reverse these, specifically focusing on noncoding regions of the genome and the tumor cell immune response.
Research includes the evaluation of host immunity and pathogenesis of Encephalitozoan cuniculi. Additional projects focus on long-term immunity against toxoplasmosis, development and maintenance of CD8+ T cell immunity, and vaccine targets to prevent toxoplasmosis.
Dr. Lynch's research explores antibody responses to virus infection and vaccination. Her lab investigates the characteristics of neutralizing antibodies as potential therapeutic agents against HIV infection as well as investigating ways to promote their production through vaccination. The Lynch lab…
Research topics include intravenous mesenchymal stromal cell therapy for inflammatory bowel disease; adoptive immunotherapy for glioblastoma, leukemia, and lymphoma; cellular therapy for sickle cell disease; therapies for HIV; and cell-based immune therapeutics in hematology.
Research interests include rehabilitation robotics, medical robotics, medical device development, minimally invasive interventions, and image-guided navigation.
Research addresses how genetic embryonic neurodevelopmental programs pattern development of circuitry of the limbic system. Projects also examine the consequences of when these processes go awry, resulting in neurodevelopmental disorders such as autism spectrum disorders.
Research examines cell enhancement, technologies for immunotherapy, and immune cell therapy for cancer and opportunistic infections.
Research interests include neuroimaging, inborn errors of metabolism, and neurogenetics.
Research interests include pharmacokinetic modeling, Cystic Fibrosis, and the airway microbiome.