Lopa Mishra Inducted into the Association of American Physicians

Congratulations to Lopa Mishra, MD, director of the Center for Translational Medicine and professor of surgery at the George Washington University School of Medicine and Health Sciences, for her induction into the Association of American Physicians (AAP).

AAP, founded in 1885, is an elected society of leading physician who are pioneers in medicine and contribute in an impactful manner to improve health. Members of the organization include Nobel laureates, along with members of the National Academy of Sciences and the Institute of Medicine.

“It is a true honor to be accepted as a member of the Association of American Physicians and to be part of an organization made up of so many remarkable and distinguished colleagues,” Mishra said.

Mishra discovered new regulators of the TGF-β superfamily. She identified a key role for TGF-β signaling in maintaining gut stem cell homeostasis, connecting TGF-β dysfunction to Beckwith Wiedemann Syndrome, which is a human cancer stem cell disorder. Mishra linked loss of TGF-β signaling with impaired DNA repair, and alcohol and clinical radiation treatment susceptibility. Her integration of the studies with The Cancer Genome Atlas (TCGA) has led to clinical trials targeting TGF-β in cancer.

Prior to her move to Washington, D.C., Mishra served as chair and professor of the Department of Gastroenterology, Hepatology, and Nutrition at the University of Texas MD Anderson Cancer Center. She also previously served as the director of digestive diseases program with surgery at the Department of Veteran Affairs Medical Center. In 2003, she was elected as a member of the American Society of Clinical Investigation, and in 2016, she was elected as a fellow of the American Association of the Advancement of Science.

Mishra will be inducted into AAP at a formal dinner on April 6 in Chicago.

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