Matthew Kay, DSBME

Professor
Primary Department
Biomedical Engineering
Affiliation
School of Engineering and Applied Science
Research Interests

Recent projects address metabolism and electrophysiology during hypoxia, ischemia, and heart failure. One project examines how chronic selective activation of hypothalamic oxytocin neurons improves cardiac function and favorably alters indices of cardiac ischemia and damage that occurs in heart failure.

Keywords

Oxytocin, Sarcolemma, Cancer Engineering, Myocardial Ischemia, Membrane Potential, Mitochondrial, Myocardium, Heart Failure, Hypoxia, Neurons, Electrophysiology,

Research Level
T0 / T1: Basic Science Discovery and Initial Translation to Humans
Research Method(s)
  • Fluorescence imaging of mitochondrial NADH
  • Sarcolemma membrane potential
  • Intracellular calcium
  • Myocardial absorbance assessments of mitochondrial ETC chromophore redox state