Dr. Sen’s basic research interest involves behavior (survival and differentiation) of human adult stem cells in hyperglycemia. His current research projects include: the effect of exercise, incretins & glucose transport inhibitors and artificial sweeteners on endothelial function and endothelial progenitor cells (EPCs) in patients with Prediabetes and type 2 diabetes. The Sen Lab is also studying use of genetically modified EPCs and mesenchymal stromal cells (MSCs) in mouse models of diabetes complications such as cardiovascular disease, chronic kidney disease and peripheral vascular disease.
Diabetes, Insulin Resistance, Apoptosis, Hyperglycemia, Renal Insufficiency, Adult Stem Cells, Peripheral Vascular Diseases, Cardiology, Endocrinology