Current Clinical Research Trials for Myasthenia Gravis

Researchers at The GW Medical Faculty Associate’s Department of Neurology are conducting clinical research trials to learn more about treating myasthenia Gravis (MG). 

Clinical research trials search for new ways to prevent, understand and/or treat disease. The goal of these trials is to see if a new treatment, procedure or device works and is safe to use.  Participating in a research trial, as either a healthy volunteer or a patient volunteer, is an opportunity to help researchers find better treatments for others in the future.

The following are clinical research trials specific to myasthenia gravis:

 

 

RA101495-02.201 gMG

Title of Research Trial: A Phase 2, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety, Tolerability, and Preliminary Efficacy of RA101495 in Subjects with Generalized Myasthenia Gravis

Principal Investigator: Henry Kaminski, M.D.

Status of Research Trial: Closed to enrollment

Sponsor of Research Trial: Ra Pharmaceuticals, Inc. 

Description of Research Trial: 

The purpose of the study is to evaluate the safety and efficacy of RA101495 in patients with generalized Myasthenia Gravis (gMG). Subjects will be randomized in a 1:1:1 ratio to receive daily SC doses of 0.1 mg/kg RA101495, 0.3 mg/kg RA101495, or matching placebo for 12 weeks.

Research Trial Contact Information:  For more information, interested participants and clinicians may contact the Neurology Clinical Research Unit at neurostudies@mfa.gwu.edu.

 

Exploratory Study of Biomarkers Predicting Response to Immunosuppressive in Myasthenia Gravis 

Principal Investigator: Henry Kaminski, M.D.

Status of Research Trial: Active, currently recruiting

Sponsor of Research Trial: The George Washington University

Description of Research Trial: This is an exploratory pilot study that will aim to describe the immunologic profiles of MG patients receiving MG treatment.

Research Trial Contact Information:  For more information, interested participants and clinicians may contact the Neurology Clinical Research Unit at neurostudies@mfa.gwu.edu.

 

MMMG: Molecular Markers of Myasthenia Gravis 

Principal Investigator: Henry Kaminski, M.D.

Status of Research Trial: Active, currently recruiting

Sponsor of Research Trial: The George Washington University

Research Trial Contact Information:  For more information, interested participants and clinicians may contact the Neurology Clinical Research Unit at neurostudies@mfa.gwu.edu.