R. Brad Jones, Ph.D.
Assistant Professor of Microbiology, Immunology and Tropical Medicine
Brad Jones, Ph.D., joined the George Washington University in May 2015 as Assistant Professor in the Department of Microbiology, Immunology and Tropical Medicine. He is an immunovirologist with considerable experience in studying the cellular immune response to acute and chronic HIV infection.
Dr. Jones received his Bachelor’s degree in Molecular Biology from Simon Fraser University in Vancouver in 2004. During his graduate studies in the laboratory of Dr. Mario Ostrowski at the University of Toronto, he identified a novel mechanism by which HIV infection drives immune cell dysfunction (Tim-3), and explored human endogenous retroviruses (HERVs) as novel targets for HIV vaccines.
After obtaining a Ph.D. in Immunology in 2011, Dr. Jones left Canada and joined the laboratories of Drs. Bruce Walker and Darrell Irvine at the Ragon Institute of MGH, MIT and Harvard in Boston as a Banting Fellow. During his post-doctoral studies at the Ragon Institute, he discovered that the histone deacetylase inhibitors under development for HIV cure therapeutics have the potential to impair the abilities of HIV-specific T-cells to eliminate infected cells. He went on to develop and refine a number of novel assays to assess the impacts of latency reversing agents on T-cell function, and worked on harnessing a new technology to enhance the ability of T cells to detect and kill latently HIV infected cells.
Dr. Jones has now embarked upon an independent research career as an Assistant Professor at MITM, where he intends to leverage his past experience to study means by which to optimally harness cytotoxic T-cell responses to contribute to HIV eradication.