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Jeffrey Williams, Anna McLean, Jalil Ahari, Arun Jose, Georges Al-Helou, Italo Ibi, Farzad Najam, Guillermo Gutierrez
Decreases in Mixed Venous Blood O2 Saturation in Cardiac Surgery Patients Following Extubation
Journal of Intensive Care Medicine, ePub Nov 2017 doi: 10.1177/088506661774143, J Intensive Care Med 2020 Mar;35(3):264-269. doi: 10.1177/0885066617741435

Babak Sarani, Mary Baginsky, RD, CNSC
A Volume-Based Enteral Nutrition Support Regimen Improves Caloric Delivery but May Not Affect Clinical Outcomes in Critically Ill Patients
JPEN J Parenter Enteral Nutr. 2017 May;41(4):607-611



Chawla LS, Toma I, Davison D, Vaziri K, Lee J, Lucas R, Seneff MG, Nyhan A, McCaffrey TA.
Acute appendicitis: transcript profiling of blood identifies promising biomarkers and potential underlying processes
BMC Med Genomics. 2016 Jul 15;9(1):40.



Koyner JL, Davison DL, Brasha-Mitchell E, Chalikonda DM, Arthur JM, Shaw AD, Tumlin JA, Trevino SA, Bennett MR, Kimmel PL, Seneff MG, Chawla LS.
Furosemide Stress Test and Biomarkers for the Prediction of AKI Severity.
J Am Soc Nephrol. 2015 Aug;26(8):2023-31



Chawla LS, Busse L, Brasha-Mitchell E, Davison D, Honiq J, Alotaibi Z, Seneff MG.
Intravenous angiotensin II for the treatment of high-output shock (ATHOS trial): a pilot study.
Crit Care. 2014 Oct 6;18(5):534

Brasha-Mitchell E, Collins A, Shehu L, Seneff MG, Patel SS, Chawla LS.
Safety and dose-finding study of activated protein C (drotrecogin alfa activated) as an anticoagulant in end-stage renal disease patients treated with hemodialysis. Blood Purif.



Chawla LS, Davison DL, Brasha-Mitchell E, Koyner JL, Arthur JM, Shaw AD, Tumlin JA, Trevino SA, Kimmel PL, Seneff MG.
Development and standardization of a furosemide stress test to predict the severity of acute kidney injury.
Crit Care. 2013 Sep 20



Davison DL, Terek M, Chawla LS.
Neurogenic pulmonary edema.
Crit Care. 2012 Mar 20;16(2):212. PMID:22429697

Chawla LS, Zhao Y, Lough FC, Schroeder E, Seneff MG, Brennan JM.
Off-pump versus on-pump coronary artery bypass grafting outcomes stratified by preoperative renal function.
J Am Soc Nephrol. 2012 Aug;23(8):1389-97.

Davison DL, Chawla LS, Selassie L, Tevar R, Junker C, Seneff MG.
Neurogenic Pulmonary Edema: Successful Treatment With IV Phentolamine.
Chest. 2012 Mar;141(3):793-5. PMID: 22396565

Davison DL, Patel K, Chawla LS
Hemodynamic Monitoring in the Critically Ill: Spanning the Range of Kidney Function.
Am J Kidney Dis. 2012 Mar 1.PMID: 22386582



Steve Allen, Daniel Holena, Maureen McCunn, Benjamin Kohl and Babak Sarani
A Review of the Fundamental Principles and Evidence Base in the Use of Extracorporeal Membrane Oxygenation (ECMO) in Critically Ill Adult Patients
J Intensive Care Med 2011 26: 13



Chawla LS, Nader A, Nelson T, Govindji T, Wilson R, Szlyk S, Nguyen A, Junker C, Seneff MG.
Utilization of base deficit and reliability of base deficit as a surrogate for serum lactate in the peri-operative setting.
BMC Anesthesiol. 2010 Sep 9;10:16

Davison DL, Chawla LS, Selassie L, Jones EM, McHone KC, Vota AR, Junker C, Sateri S, Seneff MG
Femoral-based central venous oxygen saturation is not a reliable substitute for subclavian/internal jugular-based central venous oxygen saturation in patients who are critically ill.
Chest. 2010 Jul;138(1):76-83. Epub 2010 Apr 23.



Chawla LS, Akst S, Junker C, Jacobs B, Seneff MG.
Surges of electroencephalogram activity at the time of death: a case series.
J Palliat Med. 2009 Dec;12(12):1095-100

DeBacker D, Marx G , Tan, A, Junker CD , Van Nuffelen M, Hüter L, Ching W, Michard F, Vincent JL
Arterial pressure-based cardiac output monitoring: a multicentre validation of the 3 rd generation software in septic patients
J Neurosci. 30(12): 4325-37.



Chawla LS. Jagasia D. Abell LM. Seneff MG. Egan M. Danino N. Nguyen A. Ally M. Kimmel PL. Junker C
Anion gap, anion gap corrected for albumin, and base deficit fail to accurately diagnose clinically significant hyperlactatemia in critically ill patients.
Nat Neuroscience 11(1): 72-9.

Junker CD, Seneff MG, Chawla LS, Akst SA, Davison DL, Hatib FS
Reliable detection of peripheral decoupling leads to improved cardiac output accuracy in unstable patients
Poster Presentation ESICM September 2008 Lisbon, Portugal

Chawla LS.
The expanding role of the nephrologist in the intensive care unit.
Clin J Am Soc Nephrol . 2008 Mar; 3 ( 2 ): 545

Chawla LS. Shih S. Davison D. Junker C. Seneff MG.
Anion gap, anion gap corrected for albumin, base deficit and unmeasured anions in critically ill patients: implications on the assessment of metabolic acidosis and the diagnosis of hyperlactatemia.
BMC Emergency Medicine. 8:18, 2008.

Junker CD, Seneff MG, Chawla LS, Akst SA, Davison DL.
Pilot Study of Novel Indicator for Detecting Extreme hyperdynamic Conditions in Severe Sepsis
Poster Presentation SCCM Honolulu, Hawaii February 2008

Davison D, Junker C.
Advances in critical care for the nephrologist: hemodynamic monitoring and volume management.
Clin J Am Soc Nephrol. 2008 Mar;3(2):554-61.PMID: 18256382

Herget-Rosenthal S, Saner F, Chawla LS.
Approach to hemodynamic shock and vasopressors.
Clin J Am Soc Nephrol2008 Mar; 3 ( 2 ): 546-53 Epub 2008 Feb 6. PMID: 18256381



Chawla LS.
Evolving paradigms in acute kidney injury.
Crit Care Med . 2007 Dec; 35 ( 12 ): 2866-7 . PMID: 18043210

Shokoohi H, Smith J, Holmes A, Abell B.
Bilateral Compartment Syndrome as a Result of Inferior Vena Cava Filter Thrombosis.
Ann Emerg Med. 2007 Oct 13; PMID: 17933429

Jha V, Gutierrez G.
Severe sepsis and septic shock: should blood be transfused to raise mixed venous oxygen saturation?
Ann Emerg Med. 2007 Oct 13; PMID: 17933429

Chawla LS, Seneff MG, Nelson DR, Williams M, Levy H, Kimmel PL, Macias WL.
Elevated plasma concentrations of IL-6 and elevated APACHE II score predict acute kidney injury in patients with severe sepsis.
Clin J Am Soc Nephrol . 2007 Jan; 2 ( 1 ): 22-30



Gutierrez G, Jha V.
Future shock?
Crit Care Med. 2006 Jun;34(6):1817-8. PMID: 16714980

Seneff MG
Comparing thermodilution and fick cardiac outputs: should I buy an edsel or a yugo?
J Intensive Care Med. 2006 Mar-Apr;21(2):99-100. PMID: 16537752

Ben-Amotz D, Honig JM.
Average entropy dissipation in irreversible mesoscopic processes.
Phys Rev Lett. 2006 Jan 20;96(2):020602. 2006 Jan 20.



Chawla LS. Abell L. Mazhari R. Egan M., Kadambi N, Burke HB, Junker C, Seneff MG, Kimmel PL.
Identifying critically ill patients at high risk for developing acute renal failure: a pilot study.
Kidney Int . 2005 Nov; 68 ( 5 ): 2274-80 . PMID: 16221229

Guillermo Gutierrez
Lactic Acidosis
Crit Care Med 2005 Vol. 33, No. 10

Gutierrez G, Chawla LS, Seneff MG, Katz NM, Zia H.
Lactate concentration gradient from right atrium to pulmonary artery.
Crit Care . 2005 Aug; 9 ( 4 ): R425-9 . PMID: 16137356

Stein LF, Zisman G, Rapelyea JA, Schwartz AM, Abell B, Brem RF.
Lobular carcinoma in situ of the breast presenting as a mass.
AJR Am J Roentgenol. 2005 Jun;184(6):1799-801.

Chawla LS, Georgescu F, Abell B, Seneff MG, Kimmel PL.
Modification of continuous venovenous hemodiafiltration with single-pass albumin dialysate allows for removal of serum bilirubin.
Am J Kidney Dis . 2005 Mar; 45 ( 3 ): (No PDF Available)



Chawla LS, Zia H, Gutierrez G, Katz NM, Seneff MG, Shah M.
Lack of equivalence between central and mixed venous oxygen saturation.
Chest . 2004 Dec; 126 ( 6 ): 1891-6 . PMID: 15596689

Chawla LS, Moore G, Seneff MG.
Incomplete reversal of enoxaparin toxicity by protamine: implications of renal insufficiency, obesity, and low molecular weight heparin sulfate content.
Obes Surg . 2004 May; 14 ( 5 ): 695-8 . (Abstract, No PDF Available) >



Mbonu CC, Davison DL, El-Jazzar KM, Simon GL.
Clostridium difficile colitis associated with hemolytic-uremic syndrome.
Am J Kidney Dis. 2003 May;41(5):E14. PMID: 12778432.

Kimmel PL, Chawla LS, Amarasinghe A, Peterson RA, Weihs KL, Simmens SJ, Alleyne S, et al.
Anthropometric measures, cytokines and survival in haemodialysis patients.
Nephrol Dial Transplant . 2003 Feb; 18 ( 2 ): 326-32 . PMID: 12543888



Anwar N, Chawla LS, Lew SQ.
Emphysematous pyelitis presenting as an acute abdomen in an end-stage renal disease patient treated with peritoneal dialysis.
Am J Kidney Dis . 2002 Oct; 40 ( 4 ): E13 . PMID: 12324934

Junker C, Zimmerman JE, Alzola C, Draper EA, Wagner DP.
A multicenter description of intermediate-care patients: comparison with ICU low-risk monitor patients.
Chest. 2002 Apr;121(4):1253-61. PMID: 11948061



Kimmel PL, Langman CB, Bognar B, Faugere MC, Chawla LS, Watkins DW, Malluche HH.
Zinc nutritional status modifies renal osteodystrophy in uremic rats.
Clin Nephrol . 2001 Dec; 56 ( 6 ): 445-58 . (Abstract, No PDF Available)

Chawla LS, Chegini S, Thomas JW, Guzman NJ.
Hemodialysis central venous catheter tip fracture with embolization into the pulmonary artery.
Am J Kidney Dis . 2001 Dec; 38 ( 6 ): 1311-5 . PMID: 11728966

Rosenberg AL, Seneff MG, Atiyeh L, Wagner R, Bojanowski L, Zimmerman JE.
The importance of bacterial sepsis in intensive care unit patients with acquired immunodeficiency syndrome: implications for future care in the age of increasing antiretroviral resistance.
Crit Care Med. 2001 Mar;29(3):548-56.



Seneff MG, Wagner D, Thompson D, Honeycutt C, Silver MR.
The impact of long-term acute-care facilities on the outcome and cost of care for patients undergoing prolonged mechanical ventilation.
Crit Care Med. 2000 Feb;28(2):342-50.



Zimmerman JE, Seneff MG, Sun X, Wagner DP, Knaus WA.
Evaluating laboratory usage in the intensive care unit: patient and institutional characteristics that influence frequency of blood sampling.
Crit Care Med. 1997 May;25(5):737-48.



Seneff MG, Zimmerman JE, Knaus WA, Wagner DP, Draper EA.
Predicting the duration of mechanical ventilation. The importance of disease and patient characteristics.
Chest. 1996 Aug;110(2):469-79.

Zimmerman JE, Wagner DP, Seneff MG, Becker RB, Sun X, Knaus WA.
Intensive care unit admissions with cirrhosis: risk-stratifying patient groups and predicting individual survival.
Hepatology. 1996 Jun;23(6):1393-401.



Seneff MG, Wagner DP, Wagner RP, Zimmerman JE, Knaus WA.
Hospital and 1-year survival of patients admitted to intensive care units with acute exacerbation of chronic obstructive pulmonary disease.
JAMA. 1995 Dec 20;274(23):1852-7.

Seneff MG, Mathews RA.
Use of haloperidol infusions to control delirium in critically ill adults.
Ann Pharmacother. 1995 Jul-Aug;29(7-8):690-3(Abstract, No PDF Available)

Becker RB, Zimmerman JE, Knaus WA, Wagner DP, Seneff MG, Draper EA, et al.
The use of APACHE III to evaluate ICU length of stay, resource use, and mortality after coronary artery by-pass surgery.
J Cardiovasc Surg (Torino). 1995 Feb;36(1):1-11. (Abstract, NO PDF Available)

Gilbert TB, Seneff MG, Becker RB.
Facilitation of internal jugular venous cannulation using an audio-guided Doppler ultrasound vascular access device: results from a prospective, dual-center, randomized, crossover clinical study.
Crit Care Med. 1995 Jan;23(1):60-5



Williams JF, Seneff MG, Friedman BC, McGrath BJ, Gregg R, Sunner J, Zimmerman JE.
Use of femoral venous catheters in critically ill adults: prospective study.
Crit Care Med. 1991 Apr;19(4):550-3.



Seneff MG, Corwin RW, Gold LH, Irwin RS.
Complications associated with thoracocentesis.
Chest. 1986 Jul;90(1):97-100. PMID: 3522123