Our laboratory is interested in how inflammation protects against pathogens and other noxious stimuli and yet can paradoxically harm the host through secondary effects such as carcinogenesis. The genitourinary tract is our model system. We are examining anti-pathogenic inflammation induced by bacteria such as uropathogenic E. coli. Chronic inflammation-mediated carcinogenesis is being studied using models of nitrosamine and Schistosoma haematobium exposure. Through our research, we seek to better understand inflammation and harness its potential for human benefit.
Besides studying the basic biology of genitourinary inflammation and infection, we are also collaborating with the CHARM lab at Stanford to develop better minimally invasive surgical techniques for children with conditions predisposing them to urinary tract infections.
We are part of the Stanford Department of Urology and an affiliated member of the Bio-X, Stanford Immunology, and Institute for Immunity, Transplantation, and Infection interdisciplinary programs at Stanford. More »