Publications

* Full text publications can be downloaded at: ResearchGate


Zhang JW, Liu WW, McCaffrey TA, He XQ, Liang WY, Chen XH, Feng XR, Wang L, Fu SW and Liu ML. Predictors of high on-aspirin platelet reactivity in elderly patients with coronary artery disease. Clin Interv Aging. 2017 Aug 10;12:1271-1279. doi: 10.2147/CIA.S138592. eCollection 2017.

Zhang JW, Liu TF, Chen XH, Liang WY, Feng XR, Wang L, Fu SW, McCaffrey TA and Liu ML. Validation of aspirin response-related transcripts in patients with coronary artery disease and preliminary investigation on CMTM5 function. Gene. 2017 Aug 15;624:56-65. doi: 10.1016/j.gene.2017.04.041. Epub 2017 Apr 28.

Fu SW, Kirolikar SP, Ginsburg E, Tan X, Schwartz A, Simmens SJ, Man Y-G, Pinzone JJ, Teal C, Awate A, Vonderhaar BK and Berg PE. Beta protein 1 homeoprotein induces cell growth and estrogen-independent tumorigenesis by binding to the estrogen receptor in breast cancer.  Oncotarget.  2016 July 16. doi: 10.18632/oncotarget.10633. [Epub ahead of print]

Tan X, Wu X, Ren S, Wang H, Li Z, Alshenawy W, Li W, Cui J, Luo G, Siegel SS, Fu SW and Lu Y. A point mutation in DNA polymerase β (POLB) gene is associated with increased progesterone receptor (PR) expression and intraperitoneal metastasis in gastric cancer. J Cancer. 2016, 7(11):1472-1480. doi:10.7150/jca.14844. 

Wang M, Wang X, Fu SW, Liu X, Jin T, Kang H, Ma X, Lin S, Guan H, Zhang S, Liu K, Dai C, Zhu Y and Dai Z. Single-nucleotide polymorphisms in PSCA and the risk of breast cancer in a Chinese population. Oncotarget. 2016 Mar 30. doi: 10.18632/oncotarget.8491. [Epub ahead of print]

Liu X, Wang X, Fu SW, Wang M, Kang H, Guan H, Zhang S, Liu S, Liu K, Feng Y, Dai C and Dai Z. Genetic association of deleted in colorectal carcinoma variants with breast cancer risk: A case-control study. Oncotarget.  2016 April 26 doi: 10.18632/oncotarget.9024. [Epub ahead of print]

Fu SW, Lee W, Coffey C, Lean A, Wu X, Tan X, Man Y and Brem RF. miRNA as potential biomarkers in early breast cancer detection following mammography. Cell Biosci. 6:DOI:10.1186/s13578-016-0071-0, 2016.

Tan X, Fu Y, Chen L, Lee W, Lai Y, Rezaei K, Tabbara S, Latham P, Teal CB, Man G, Siegel RS, Brem RF and Fu SW.  miR-671-5p inhibits epithelial-to-mesenchymal transition by downregulating FOXM1 expression in breast cancer. Oncotarget. 6:DOI:10.18632. Nov, 18, 2015.

Wu X, Tan X and Fu SW. May circulating microRNAs be gastric cancer diagnostic biomarkers? J Cancer. 6(12):1206-1213, 2015.

An S, Tan X and Fu SW. Deregulated miRNAs in Triple Negative Breast Cancer. New Approaches combating Cancer & Aging. 2(1): 19-34, 2015.

Liu T, Zhang J, Chen X, Feng X, Fu SW, McCaffrey TA and Liu M. Comparison between urinary 11-dehydrothromboxane B2 detection and platelet Light Transmission Aggregometry (LTA) assays for evaluating aspirin response in elderly patients with coronary artery disease. Gene. 571(1):23-7,2015.

Tan X, Wang H, Luo G, Ren S, Li W, Cui J, Gill H, Fu SW and Lu Y. Clinical Significance of a Point Mutation in DNA Polymerase Beta (POLB) Gene in Gastric Cancer. Int J Biol Sci. 11(2):144-155, 2015.

Zhu W, Wang M, Fu Y, Castro NJ, Fu SW, Zhang LG. Engineering a Biomimetic Three-dimensional Nanostructured Bone Model for Breast Cancer Bone Metastasis Study. Acta Biomater. 14:164-174, 2015. 

Tan X, Fu Y, Chen L, An S, Lee W, Rezaei K, Man Y-G , Brem RF and Fu, SW. miR-638 Mediated Regulation of BRCA1 Affects DNA Repair and Sensitivity to UV and Cisplatin in Triple Negative Breast Cancer. Breast Cancer Res. 16(5):435, 2014. 

Shen F, Mo M-H, Chen L, An S, Tan X, Fu Y, Rezaei K, Wang Z, Zhang Z, Fu SW. MicroRNA-21 Down-regulates Rb1 Expression by Targeting PDCD4 in Retinoblastoma. J Cancer. 5(9): 804-812, 2014. 

Song G, Hsiao H, Wang JL, Mannion C, Stojadinovic A, Avital I, Fu SW, Mason J, Chen W, Jewett A, Li H, Man YG. Differential Impact of Tumor-infiltrating Immune Cells on Basal and Luminal Cells: Implications for Tumor Invasion and Metastasis. Anticancer Res. 34(11):6363-80, 2014. 

Man Y-G, Wang J, Mason J, Mannion C, Fu SW, Jewett A, Avital I and Stojadinovic A. Can Current Cell Sorting Methods Capture Cancer Invasion and Metastasis-causing Stem Cells? New Approaches combating Cancer & Aging 1(1): 1-23, 2014.

McCaffrey TA, Tziros C, Lewis J, Katz R, Siegel R, Weglicki W, Kramer J, Mak IT, Toma I, Chen L, Benas E, Lowitt A, Rao S, Witkin L, Lian Y, Lai Y, Yang Z and Fu SW. Genomic Profiling Reveals the Potential Role of TCL1A and MDR1 Deficiency in Chemotherapy-Induced Cardiotoxicity. Int J Biol Sci. 9(4):350-360, 2013. 

Fallahi P, Katz R, Toma I, Li R, Reiner J, Vanhouten K, Carpio L, Marshall L, Lian Y, Bupp S, Fu SW, Rickles F, Leitenberg D, Lai Y, Weksler BB, Rebling F, Yang Z, McCaffrey TA. Aspirin Insensitive Thrombophilia: Transcript Profiling of Blood Identifies Platelet Abnormalities and HLA Restriction. Gene. 520 (2):131-138, 2013. 

Chen L, Li Y, Fu Y, Peng J, Mo M-H, Stamatakos M, Teal CB, Brem RF, Stojadinovic A, Grinkemeyer M, McCaffrey TA, Man YG and Fu SW. Role of Deregulated microRNAs in Breast Cancer Progression Using FFPE Tissue. PLoS ONE 8(1): e54213, 2013. 

Moran-Atkin E, Brody F, Fu SW and Rojkind M. Changes in GIP gene expression following bariatric surgery. Surg Endosc. 27(7):2492-7, 2013. 

Edwards CR, Hindle AK, Latham PS, Fu SW, Brody FJ. Resistin Expression Correlates with Steatohepatitis in Morbidly Obese Patients. Surg Endosc. 27(4):1310-4, 2013.

Mo MH, Chen L, Fu Y, Wang W, Fu SW. Cell-free Circulating miRNA Biomarkers in Cancer. J Cancer. 3:432-48, 2012. 

Song G, Ren J, Stojadinovic A, Chen W, Sahab Z, Fu SW and Man YG. Conjunction of Tumor Cells with Lymphocytes: Implications for Tumor Invasion and Metastasis. Cancer Epidemiol. 36(4):354-63, 2012. 

Narasipura SD, Henderson LJ, Fu SW, Chen L, Kashanchi F and Al-Harthi L. Role of β-Catenin and TCF/LEF Family Members in Transcriptional Activity of HIV in Astrocytes. J Virol. 86(4):1911-21, 2012. 

Man YG, Fu SW, Liu AJ, Stojadinovic A, Izadjoo M, Chen L, Gardner WA. Aberrant expression of chromogranin A, miR-146a, and miR-146b-5p in prostate structures with focally disrupted basal cell layers: an early sign of invasion and hormone-refractory cancer? Cancer Genomics Proteomics. 8(5):235-44, 2011. 

Reyes-Gordillo K, Shah R, Popratiloff A, Fu SW, Kindle AK, Brody F and Rojkind M. Thymosin-β4 (Tβ4) blunts PDGF-Dependent Phosphorylation and Binding of AKT to Actin in Hepatic Stellate Cells. Am J Pathol. 178(5):2100-8, 2011. 

Fu SW, Chen L, Man Y-G. miRNA Biomarkers in Breast Cancer Detection and Management. J Cancer 2:116-122, 2011. 

Heydarian M, Dowser A, Guendel I, Duyne RV, McCaffrey T, Fu SW, Kehn-Hall K and Kashanchi F. Features of HTLV-1 transcriptional and chromatin remodeling dynamics emerge from ChIP-chip analysis. Retrovirology. 8(Suppl 1): A181. 2011. 

Edwards C, Hindle AK, Fu S, Brody F. Downregulation of leptin and resistin expression in blood following bariatric surgery. Surg Endosc. 25(6):1962-8, 2011. 

Hindle AK, Edwards C, Mendonsa A, Rojkind M, McCaffrey T, Fu S and Brody F. Adiponectin but not leptin is involved in early hepatic disease in morbidly obese patients. Surg Endosc. 24(7):1547-51, 2010. 

Fu Y, Lian Y, Kim KS, Zhang L, Hindle AK, Brody F, Siegel RS, McCaffrey TA, Fu SW. BP1 homeoprotein enhances metastatic potential in ER-negative breast cancer. J Cancer. 24;1:54-62, 2010. 

Kluk BJ, Fu Y, Formolo TA, Zhang L, Hindle AK, Man YG, Siegel RS, Berg PE, Deng C, McCaffrey TA, Fu SW. BP1, an isoform of DLX4 homeoprotein, negatively regulates BRCA1 in sporadic breast cancer. Int J Biol Sci. 6(5):513-24, 2010.

Li DQ, Pakala SB, Reddy SD, Ohshiro K, Peng SH, Lian Y, Fu SW, Kumar R. Revelation of p53-independent function of MTA1 in DNA damage response via modulation of p21WAF1-PCNA pathway. J Biol Chem. 285(13):10044-52, 2010. 

Hindle AK, Edwards C, McCaffrey T, Fu S and Brody F. Reactivation of adiponectin expression in obese patients after bariatric surgery. Surg Endosc. 24(6):1367-73, 2010. 

Kirkel D, Lin TW, Fu SW, Dlott JS, Sahud MA, McCaffrey T, Rickles FR. Asymptomatic factor VII deficiency: gene analysis and structure-function relationships. Blood Coagul Fibrinolysis. 21(1):91-4, 2010. 

Hindle AK, Edwards C, McCaffrey T, Fu S and Brody F. Identification of cardiovascular genes in omentum from morbidly obese patients with type 2 diabetes. Int J Obes. 34(6):1020-7, 2010. 

Song Y, Dang C, Fu Y, Lian Y, Hottel J, Li X, McCaffrey T, Fu SW. Genome-wide analysis of BP1 transcriptional targets in breast cancer cell line Hs578T. Int J Biol Sci. 5(1):1-12. 2009. 

Klaes Z, Winograd R, Davis J, Carpio L, Hildreth R, Heydarian M, Fu S, McCaffrey T, Meiri E, Ayash-Rashkovsky M, Gilad S, Bentwich Z, Kashanchi F. HIV-1 TAR miRNA protects against apoptosis by altering cellular gene expression. Retrovirology. 6:18. 2009. 

Poola I, Abraham J, Marshalleck JJ, Yue Q, Fu SW, Viswanath L, Sharma N, Hill R, Dewitty RL, Bonney G. Molecular constitution of breast but not other reproductive tissues is rich in growth promoting molecules: a possible link to highest incidence of tumor growths. FEBS Lett. 583(18):3069-75, 2009. 

Hindle AK, Koury J, McCaffrey T, Fu SW, Brody F. Dysregulation of gene expression within the peroxisome proliferator activated receptor pathway in morbidly obese patients. Surg Endosc. 23(6):1292-7, 2009. 

Hindle AK, Brody F, Tevar R, Kluk B, Hill S, McCaffrey T, Fu S. TCF7L2 expression in diabetic patients undergoing bariatric surgery. Surg Endosc. 23(4):700-4, 2009. 

Awwad RT, Do K, Stevenson H, Fu SW, Lo-Coco F, Costello M, Campbell CL, Berg PE. Overexpression of BP1, a homeobox gene, is associated with resistance to all-trans retinoic acid in acute promyelocytic leukemia cells. Ann Hematol 87(3): 195-203, 2008. 

Stevenson HS, Fu SW, Pinzone JJ, Rheey J, Simmens SJ, Berg PE. BP1 transcriptionally activates bcl-2 and inhibits TNFalpha-induced cell death in MCF7 breast cancer cells. Breast Cancer Res 9(5): R60, 2008. 

Brody F, Hill S, Celenski S, Kar R, Kluk B, Pinzone J and Fu S. Expression of ectonucleotide   pyrophosphate phosphodiesterase and peroxisome proliferator activated receptor gamma in morbidly obese patients. Surg Endosc. 21(6):941-4, 2007. 

Song YC, Fu SD, Wen XP, Ma ZH, Dang CX.  Expression and Significance of BP1 Gene and Cyclin D1 Gene in Breast Cancer." Ai Zheng 26(7): 709-14, 2007. 

Kehn K, Berro R, Alhaj A, Bottazzi ME, Yeh W-I, Klase Z, Van Duyne R, Fu S and Kashanchi F. Functional consequences of cyclin D1/BRCA1 interaction in breast cancer cells. Oncogene, 26(35):5060-9, 2007. 

Xian YS, Dang CX, Yan CX, Li HP, Fu SW, Wang ZR. Clinicopathological significance of homeobox BP1 mRNA expression in lung cancer tissue. Nan Fang Yi Ke Da Xue Xue Bao. 26(8):1173-5, 2006.

Fu, SW. Identification of cancer biomarkers using DNA microarrays. Pharmaceutical Discovery 5(7):  Supplement (The State of the Art in Microarray Technology for Biomarker Discovery). 18-21, 2005.

Man Y-G, Fu SW, Schwartz A, Pinzone JJ, Simmens, SJ, Berg PE. Expression of BP1, a novel homobox gene, correlates with breast cancer progression and invasion. Breast Cancer Res Treat. 90:241-247, 2005. 

Cahan P, Ahmad A, Burke H, Fu S, Lai Y, Florea L, Dharker N, Kobrinski T, Kale P and  McCaffrey T. List of Lists-Annotated (LOLA): A database for annotation comparison of published microarray gene lists. Gene 360(1):78-82., 2005. 

Fu SW, Schwartz A, Stevenson H, Pinzone JJ, Davenport GJ, Orenstein JM, Gutierrez P, Simmens SJ, Abraham J, Poola I, Stephan DA, Berg PE. Correlation of expression of BP1, a homeobox gene, with estrogen receptor status in breast cancer. Breast Cancer Res. 5:82-87, 2003. 

Chase MB*, Fu S*, Haga SB, Davenport G, Stevenson H, Do K, Morgan D, Mah AL, Berg PE. BP1, a homeodomain-containing isoform of DLX4, represses the beta-globin gene. Mol Cell Biol. 22:2505-14, 2002 (*Chase MB and Fu S are equal first authors). 

Fu S, Stevenson H, Strovel JW, Haga SB, Stamberg J, Do K, Berg PE.Distinct functions of two isoforms of a homeobox gene, BP1 and DLX7, in the regulation of the beta-globin gene. Gene. 278:131-9, 2001. 

Haga SB, Fu S, Karp JE, Ross DD, Hankins WD, Williams DM, Behm F, Ruscetti FW, Chang M, Smith BD, Becton D, Raimondi SC, Berg PE. BP1, a new homeobox gene, is frequently expressed in acute leukemias. Leukemia. 14: 1867-1875, 2000. 

Binion DG, Rafiee P, Ramanujam KS, Fu S, Fisher PJ, Rivera MT, Johnson CP, Otterson MF, Telford GL,  Wilson KT. Deficient iNOS in inflammatory bowel disease intestinal microvascular endothelial cells results in increased leukocyte adhesion. Free Radic Biol Med. 29(9): 881-8. 2000. 

Fu S, Ramanujam KS, Wong A, Fantry GT, Drachenberg CB, James SP, Meltzer SJ, Wilson KT. Increased expression and cellular localization of inducible nitric oxide synthase and cyclooxygenase 2 in Helicobacter pylori gastritis. Gastroenterology. 116(6):1319-29, 1999. 

Binion DG, Fu S, Ramanujam KS, Chai YC, Dweik RA, Drazba JA, Wade JG, Ziats NP, Erzurum SC, Wilson KT. iNOS expression in human intestinal microvascular endothelial cells inhibits leukocyte adhesion. Am J Physiol. 275(3 Pt 1):G592-603, 1998. 

Wilson KT, Fu S, Ramanujam KS, Meltzer SJ. Increased expression and localization of inducible nitric oxide synthase and cyclooxygenase‑2 in Barrett's Esophagus and associated adenocarcinomas. Cancer Res. 58: 2929-2934, 1998. 

Kundu N, Dorsey R, Jackson MJ, Guiterrez P, Wilson K, Fu S, Ramanujam K, Thomas E, Fulton AM. Interleukin-10 gene transfer inhibits murine mammary tumors and elevates nitric oxide. Int J Cancer. 76(5): 713-719, 1998. 

Migeon BR, Jeppesen P, Torchia BS, Fu S, Dunn MA, Axelman J, Schmeckpeper BJ, Fantes J, Zori RT, Driscoll DJ. Lack of X inactivation associated with maternal X isodisomy: evidence for a counting mechanism prior to X inactivation during human embryo genesis. Am J Hum Genet. 58: 161‑170, 1996. 

Chai J, Shen Y, Fan Y, Fu S, Qin X, Ye L, Shi H, Zhao S, Lin T,  Wu, G. Detection of Hypermethylation in affected males with fragile X syndrome by PCR assay. Acta Academiae Medicinae Scinicae. 17(1): 47‑51, 1995.

Fu S, Shen Y, Fan Y, Chai J, Qin X, Lin T, Wu, G. Unstable DNA sequences and methylation in fragile X syndrome. Chinese Medical Journal. 74(10): 611‑615, 1994.

Fu S, Shen Y. A new focus in molecular genetic study: dynamic mutation and fragile X syndrome. Medicine Abroad (Molecular Biology Branch). 16(2): 78‑82, 1994.

Wu G, Shen Y, Fu S, Lin T. Hypermethylation of FMR‑1 and dynamic mutation of (CGG)n repeats.  Medical Research Informatics. 22: 40‑42, 1994.

Fu S, Shen Y, Fan Y, Lin T, Wu G. Variable (CGG)n repeat and methylation of FMR‑1 gene in a fragile X syndrome family. Chinese J Hum Genet. 12(3): 355‑356, 1993.

Fan Y, Shen Y, Fu S, Lin T, Zhao Y, Wu G. A quick way to detect DNA methylation. Progress in Biochemistry and Biophysics. 20(6): 458‑459, 1993.