Events » Treatment Approaches & Inflammation

Treatment Approaches & Inflammation

Biomedical Cross-Disciplinary Event Series Banner
When: 
Thursday, June 25, 2020 - 7:00pm to 10:00pm
Where: 

Ross Hall, Room # ( TBA ) The George Washington University
2300 I Street NW Washington, DC 20037

Contacts: 

For more information, contact co-organizer Leigh Frame, PhD, MHS, Program Director, Integrative Medicine, and Executive Director, Office of Integrative Medicine and Health, at leighframe@gwu.edu or 202-994-0184, or co-organizer Paul Marvar, PhD, associate professor, Department of Pharmacology and Physiology, pmarvar@gwu.edu or 202-994-5584.

GW School of Medicine and Health Sciences is connecting academic research and inquiry across disciplines.

About this Event

Join us for GW Biomedical Cross-disciplinary Seminar Series: Connecting Academic Research & Inquiry Across Disciplines—a series of seminars that will explore a new cross-disciplinary topic each year. For the inaugural year, the focus is "Inflammation in Chronic Disease: Cause, Consequence, or Both?" and will address both the treatment and prevention of chronic inflammatory diseases.

This lecture is on "Treatment Approaches and Inflammation" with Vishwa Deep Dixit, DVM, PhD, is the Waldemar Von Zedtwitz Professor of Comparative Medicine and of Immunobiology at the Yale School of Medicine, and a member of the Yale Center on Research on Aging.

He studies the interaction between immune and metabolic systems with the goal of revealing targets that can be harnessed to extend the healthspan — the period of life that is free of disabilities and disease.

Dr. Dixit’s laboratory has help define the role of innate immune sensor NLRP3 inflammasome as a predominant inflammation triggering mechanism that causes systemic degenerative diseases of aging, including metabolic dysfunction. His team identified that ketone metabolite β-hydroxybutyrate, which is produced in the body during the state of fasting, serves as a therapeutic target to lower the NLRP3 inflammasome-dependent inflammatory diseases. Dixit’s laboratory has recently discovered a new cell subtype called nerve-associated macrophages. This finding highlights how the immune system plays a key role in linking the autonomic nervous system to the ability of adipose tissue to mobilize energy from fat, a mechanism that is impaired in the elderly because of inflammation.

He has received numerous awards for his research, including the Fellows Award for Research Excellence by NIH (thrice), Nathan Shock Young Investigator Awards from National Institute on Aging and Gerontological Society of America and the Young Investigator Award from the Endocrine Society. Dixit Laboratory is funded in part by NIH.

The seminar series runs from November 2019 through September 2020. It was organized by the Department of Pharmacology & Physiology and the Office of Integrative Medicine and Health. Each seminar includes a catered lunch. Registration required for lunch purposes.

The 2019-2020 seminars will focus on several areas of chronic inflammatory disease (CID) including:

  • Cancer and inflammation
  • Genomics and inflammation
  • Bioinformatics and and inflammation
  • Cardiometabolic disease and inflammation
  • Neuropsychiatric disease and inflammation
  • Precision medicine and inflammation
  • Treatment approaches and inflammation

Plus a final event on One GW Day!

The seminar series is supported by departmental funding and the generosity of Ellen J. LaBelle, MD `74, associate clinical professor of the Department of Psychiatry and Behavioral Sciences, and John Pan, MD, clinical professor, Department of Clinical Research and Leadership, and founding medical director, Office of Integrative Medicine and Health.