Ross Hall #737
Sonia Najjar, PhD
OHF John J. Kopchick Ph.D. Endowed Eminent Research Chair
Professor, Department of Biomedical Sciences
Heritage College of Osteopathic Medicine of Ohio University
Dr. Najjar laboratory has identified a role for CEACAM1 in promoting insulin clearance and suppressing hepatic fatty acid synthase activity. The lecture will focus on how lowering hepatic CEACAM1 level leads to insulin resistance and non- alcoholic fatty liver disease (NAFLD). Lowering CEACAM1 levels can also lead to steatohepatitis and fibrosis; all of which constitute key features of NASH, the progressive form of NAFLD.