Ross Hall Room 602
Contact MITM@gwu.edu with questions
Dr. McVicar’s laboratory studies the regulation of innate immune cell metabolism
and function in cancer. As a member of the Cancer and Inflammation Program,
Dr. McVicar uses a variety of cellular and molecular techniques to understand the
biology and biochemistry of a variety of receptor systems including the triggering
receptors expressed on myeloid cells (TREM) that regulate neutrophils, macrophages,
monocytes, dendritic cells and platelets, and the killer Ig-like receptors (KIR) that
regulate natural killer (NK) cells. Components of signaling cascades identified by the
laboratory are interrogated using murine models of infection and/or
inflammation-associated cancers including hepatocellular carcinoma and colorectal
cancer.
