Current Projects

The Clinical Research Program conducts studies aimed at the prevention of disease and injury by early identification of risk factors, the mitigation of the negative health consequences of disease and injury through comparative effectiveness research and the provision of treatments that quicken recovery and reduce disability. Below is a summary of current clinical research projects being conducted in our department.

 

Current Clinical Research Projects in the George Washington University Emergency Department

Study Name

Principal Investigator

Coordinator

Brief Project Description

Monotherapy Anticoagulation To expedite Home treatment of Venous Thrombo Embolism. (MATH VTE)

Dr. Andrew Meltzer

Nataly Montano

This is a prospective registry study to measure 30 day post-diagnosis readmission rate of emergency department patients diagnosed with deep vein thrombosis or pulmonary embolism (venous thromboembolism, VTE) and treated at home with apixaban.

Capsule Endoscopy for HEmorrhage in the Emergency Room (CHEER)

Dr. Andrew Meltzer

Nataly Montano

This is a randomized controlled trial examining the use of Video Capsule Endoscopy (VCE) to discharge low to moderate risk patients with suspected upper gastrointestinal bleeds from the Emergency Department.

Integrating Social Determinants of Health into Risk Adjustment Models: An Opportunity to Improve Care Coordination Strategies for Medicaid Beneficiaries

Dr. Melissa McCarthy

Paige Kulie

This is a prospective cohort study aiming to provide evidence of the value of measuring social determinants of health in the Medicaid population.

Application of Centor Critera via Telemedicine

Dr. Neal Sikka

Paige Kulie

This is a prospective cohort study to evaluate the ability of medical providers to use telemedicine to assess patients with sore throat compared to an in-person clinical evaluation. 

Intelligent surface for the inhibition of biofilms on urinary catheters

Dr. John LaFleur

Paige Kulie

This is a prospective cohort study to identify a novel means for inhibiting biofilm formation on catheter surfaces for patients with urinary tract infections.

AHL production by gut microbiota in sepsis

Dr. John LaFleur

Paige Kulie

This is a prospective cohort study to test for the presence of acylated homoserine lactones (AHLs) in the stool and blood of patients with sepsis.

Attitudes and Risk Behaviors surrounding PrEP in Patients Presenting to the Emergency Department and an Urgent Care Clinic

Dr. Natasha Powell

Paige Kulie

This is a prospective cohort study to better understand the current awareness and attitudes about pre-exposure prophylaxis (PrEP) in Washington, DC.

Using virtual reality to aid emergency drainage of peritonsillar abscess compared to standard landmark approach: A feasibility study

Dr. Neal Sikka

Paige Kulie

This is a prospective cohort study to determine whether using virtual reality 3D reconstruction of peritonsillar abscess will increase the precision in draining the abscess and decrease the rate of complications compared to the standard practice of drainage based on anatomical landmarks on physical exam.

A Randomized Controlled Trial of Biofire Film Array Gastrointestinal Panel Compared to Usual Care for Evaluation of Acute Infectious Diarrhea in the Emergency Department

Dr. Andrew Meltzer

Nataly Montano

This is a randomized controlled trial to evaluate how use of the Biofire Film Array Gastrointestinal Panel affects antibiotic utilization, clinical improvement and diagnostic yield of ED patients with suspected acute infectious diarrhea as compared to usual care.

Cannabanoid Hyperemesis Syndrome - Pilot Study

Dr. Andrew Meltzer

Nataly Montano

This is a prospective observational study to evaluate current management and symptom resolution of emergency department patients who present with Cannabanoid Hyperemesis Syndrome.

Effect of Immersive Virtual Reality Breaks on Shift-Worker Alertness

Dr. Neal Sikka

Paige Kulie

This is a prospective cohort study to evaluate whether the use of immersive virtual reality breaks during shifts can reduce stress and anxiety and increase efficiency for nurses.

Electric Scooter Pilot Study

Dr. Melissa McCarthy

Paige Kulie

This is a case-crossover study  to evaluate infrastructed affiliated with injuries sustained while riding an electric scooter or moped.

Smoking Habits of Emergency Department Patients

Dr. Melissa McCarthy

Paige Kulie

This is a cross-sectional study to understand more about the smoking habits of patients in the emergency department.