Current Projects

The Clinical Research Program conducts studies aimed at the prevention of disease and injury by early identification of risk factors, the mitigation of the negative health consequences of disease and injury through comparative effectiveness research and the provision of treatments that quicken recovery and reduce disability. Below is a summary of current clinical research projects being conducted in our department.

 

Current Clinical Research Projects in the George Washington University Emergency Department

Study Name

Principal Investigator

Coordinator

Brief Project Description

Skin Alcohol Sensor in the Emergency Room (SASSIER)

Dr. Andrew Meltzer

Maxine LeSaux

This is a prospective trial examining the use of a skin alcohol sensor to estimate blood alcohol content (BAC) in patients with suspected alcohol intoxication from the Emergency Department. This study will compare the skin alcohol sensor to blood alcohol level and /or breathalyzer. This study is in collaboration with the Li Lab of Nanophotonics and Microfluidics in the George Washington University Department of Biomedical Engineering.

Capsule Endoscopy for HEmorrhage in the Emergency Room (CHEER)

Dr. Andrew Meltzer

Maxine LeSaux

This is a randomized controlled trial examining the use of Video Capsule Endoscopy (VCE) to discharge low to moderate risk patients with suspected upper gastrointestinal bleeds from the Emergency Department.

Integrating Social Determinants of Health into Risk Adjustment Models: An Opportunity to Improve Care Coordination Strategies for Medicaid Beneficiaries

Dr. Melissa McCarthy

Paige Kulie

This is a prospective cohort study aiming to provide evidence of the value of measuring social determinants of health in the Medicaid population.

Application of Ottawa Ankle Rule via Telemedicine

Dr. Neal Sikka

Paige Kulie

This is a prospective cohort study to evaluate the ability of medical providers to use telemedicine to assess patients with ankle injuries compared to an in-person clinical evaluation. 

The use of point-of-care ultrasound to screen for venous thromboembolism in patients with atypical COPD exacerbation

Dr. Hamid Shokoohi

Paige Kulie

This is a prospective cohort study to evaluate the use of ultrasound of the legs and heart in making a diagnosis of blood clots in the lung or legs in cases of COPD exacerbation.

Sonographic Evaluation of Optic Nerve Sheath Diameter Measurements in Correlation with Magnetic Resonance Imaging in Determining an Elevated Intracranial Pressure

Dr. Hamid Shokoohi

Paige Kulie

This is a prospective cohort study to evaluate the use of ultrasound of the eyes to detect increased pressure in the brain.

Intelligent surface for the inhibition of biofilms on urinary catheters

Dr. John LaFleur

Paige Kulie

This is a prospective cohort study to identify a novel means for inhibiting biofilm formation on catheter surfaces for patients with urinary tract infections.

AHL production by gut microbiota in sepsis

Dr. John LaFleur

Paige Kulie

This is a prospective cohort study to test for the presence of acylated homoserine lactones (AHLs) in the stool and blood of patients with sepsis.

Attitudes and Risk Behaviors surrounding PrEP in Patients Presenting to the Emergency Department and an Urgent Care Clinic

Dr. Natasha Powell

Paige Kulie

This is a prospective cohort study to better understand the current awareness and attitudes about pre-exposure prophylaxis (PrEP) in Washington, DC.

Pilot project to evaluate the feasibility and effectiveness of a telehousing referral in the emergency department

Dr. Melissa McCarthy

Paige Kulie

This is a randomized controlled trial to determine the impact of a telehousing intake session on receipt of housing services and housing stability.

Using virtual reality to aid emergency drainage of peritonsillar abscess compared to standard landmark approach: A feasibility study

Dr. Neal Sikka

Paige Kulie

This is a prospective cohort study to determine whether using virtual reality 3D reconstruction of peritonsillar abscess will increase the precision in draining the abscess and decrease the rate of complications compared to the standard practice of drainage based on anatomical landmarks on physical exam.

Longitudinal Assessment of Patients Presenting to the Emergency Department with Non Life-Threatening Diseases, An Emoji-Based Study

Dr. Ali Pourmand

Paige Kulie

This is a prospective cohort study to assess patient satisfaction/attitude/general mood at different time intervals throughout an emergency department visit using emojis.

Using Text Messaging for Smoking Cessation in Medicaid

Dr. Lorien Abroms/Dr. Melissa McCarthy

Paige Kulie

This is a randomized controlled trial to find out how communication technologies can aid in smoking cessation.

A Randomized Controlled Trial of Biofire Film Array Gastrointestinal Panel Compared to Usual Care for Evaluation of Acute Infectious Diarrhea in the Emergency Department

Dr. Andrew Meltzer

Maxine LeSaux

This is a randomized controlled trial to evaluate how use of the Biofire Film Array Gastrointestinal Panel affects antibiotic utilization, clinical improvement and diagnostic yield of ED patients with suspected acute infectious diarrhea as compared to usual care.

Cannabanoid Hyperemesis Syndrome - Pilot Study

Dr. Andrew Meltzer

Maxine LeSaux

This is a prospective observational study to evaluate current management and symptom resolution of emergency department patients who present with Cannabanoid Hyperemesis Syndrome.