A recent multi-center clinical trial funded by the National Institute for Diabetes and Digestive and Kidney Diseases, revealed no significant support for the use of tamsulosin for kidney stones. The results, published in JAMA Internal Medicine, found no significant effect of patient-reported passage or capture of the stone.
“There is no known medication for helping patients pass kidney stones,” explained Andrew Meltzer, MD, associate professor of emergency medicine at the George Washington University (GW) School of Medicine and Health Sciences. Current guidelines by the American Urological Society call for all patients with stones to receive tamsulosin to help facilitate passage. “We will likely have to change the guidelines regarding which groups of patients should receive the medication,” he said.