• Rendering of cancer metastasis

Biophysical Study of Cancer Progression

The Chung Lab focuses on understanding biophysical mechanisms of cancer metastasis and identifying novel therapeutic targets. Metastasis is the leading cause of death in cancer patients. We believe that characterization and analysis of real-time movements of individual proteins and other biomolecules in living cells will bring us a greater understanding of the molecular basis of cancer initiation and progression. To this end, we use and develop various biophysical methods including single molecule tracking, cutting-edge super-resolution microscopy, and advanced statistical analyses, in conjunction with traditional biochemistry and cell biology techniques and animal models. This integrated approach allows us to reveal details of cell biological and biophysical processes that drive cancer, which cannot be uncovered using traditional methods alone.