The Chiappinelli laboratory is housed within the Department of Microbiology, Immunology, and Tropical Medicine at The George Washington University School of Medicine and Health Sciences in Washington, D.C.
Our lab focuses on the epigenetic regulation of immune signaling in cancer. Epigenetic therapy is particularly appealing as it provides a way to alter gene expression without changing the DNA itself. We study the epigenetic changes in cancer and how epigenetic drugs can reverse these, specifically focusing on noncoding regions of the genome and the tumor cell immune response.
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