The Biochemistry and Molecular Medicine Department provides a highly stimulating educative experience, immersing students in the bridging of Biochemistry, Molecular Genetics, Bioinformatics and Genomics with Translational Medicine.
Our unique multidisciplinary research program includes work on Cancer Biology, Autism, Cardiovascular Pathobiology, and Computational Genomics, unlocking the mysteries of biologic processes at the molecular and genomic level.
Our basic science-focused department approaches its centennial anniversary and we are profoundly proud of our lustrous history of academic excellence in research and education. We are eager to achieve more cross-pollination and scientific synergy both in and outside the department.
The Distinguished Researcher Award, presented to Raja Mazumder, PhD, professor of biochemistry and molecular medicine.
Dr. Alejandro Villagra has received a new NIH R01 grant entitled "Development of selective HDAC6 inhibitors to improve cancer immunotherapy”, with a total funding amount of $3,024,000 for five years. The objective of this grant is to develop and test novel epigenetic drugs with the capacity of reshaping antitumor immune responses.
This research in Briefings in Bioinformatics identifies mutational hotspots in non-coding regions from multiple cancers through whole genome sequence analysis. J P Torcivia, R Mazumder. Briefings in Bioinformatics, bbaa203, https://doi.org/10.1093/bib/bbaa203
HDAC6 plays a non-canonical role in the regulation of anti-tumor immune responses, dissemination, and invasiveness of breast cancer.
