Publications

2021

Content forthcoming

2020

Content forthcoming

2015

The effects of cocaine on HIV transcription.
Tyagi M, Weber J, Bukrinsky M, Simon GL.
J Neurovirol. 2015 Nov 16. [Epub ahead of print]

HIV infection induces structural and functional changes in high density lipoproteins.
Siegel MO, Borkowska AG, Dubrovsky L, Roth M, Welti R, Roberts AD, Parenti DM, Simon GL, Sviridov D, Simmens S, Bukrinsky M, Fitzgerald ML.
Atherosclerosis. 2015 Nov;243(1):19-29.

Lipid metabolism in patients infected with Nef-deficient HIV-1 strain.
Low H, Cheng L, Di Yacovo MS, Churchill MJ, Meikle P, Bukrinsky M, Hill AF, Sviridov D.
Atherosclerosis. 2015 Oct 30;244:22-28. 

Extracellular cyclophilins in health and disease.
Bukrinsky M.
Biochim Biophys Acta. 2015 Oct;1850(10):2087-95. Review.

Stimulation of Liver X Receptor Has Potent Anti-HIV Effects in a Humanized Mouse Model of HIV Infection.
Ramezani A, Dubrovsky L, Pushkarsky T, Sviridov D, Karandish S, Raj DS, Fitzgerald ML, Bukrinsky M.
J Pharmacol Exp Ther. 2015 Sep;354(3):376-83.

Targeting extracellular cyclophilins ameliorates disease progression in experimental biliary atresia.
Iordanskaia T, Malesevic M, Fischer G, Pushkarsky T, Bukrinsky M, Nadler E.
Mol Med. 2015 Jul 24.

Inhibition of extracellular cyclophilins with cyclosporine analog and development of atherosclerosis in apolipoprotein e-deficient mice.
Ditiatkovski M, Neelisetti VN, Cui HL, Malesevic M, Fischer G, Bukrinsky M, Sviridov D.
J Pharmacol Exp Ther. 2015 Jun;353(3):490-5.

Top

2014

Bukrinsky M.
Extracellular cyclophilins in health and disease.
Biochim Biophys Acta. 2014 Nov 18. pii: S0304-4165(14)00390-0. 

Jennelle L, Hunegnaw R, Dubrovsky L, Pushkarsky T, Fitzgerald ML, Sviridov D, Popratiloff A, Brichacek B, Bukrinsky M.
HIV-1 protein Nef inhibits activity of ATP-binding cassette transporter A1 by targeting endoplasmic reticulum chaperone calnexin.
J Biol Chem. 2014 Oct 17;289(42):28870-84.

Brichacek B, Darwish C, Popratiloff A, Dubrovsky L, Bukrinsky M.
HIV-1 infection of macrophages induces retention of cholesterol transporter ABCA1 in the endoplasmic reticulum.
AIDS Res Hum Retroviruses. 2014 Oct;30(10):947-8. 

Sviridov D, Bukrinsky M. 
Interaction of pathogens with host cholesterol metabolism.
Curr Opin Lipidol. 2014 Oct;25(5):333-8.

Cui HL, Ditiatkovski M, Kesani R, Bobryshev YV, Liu Y, Geyer M, Mukhamedova N, Bukrinsky M, Sviridov D.
HIV protein Nef causes dyslipidemia and formation of foam cells in mouse models of atherosclerosis.
FASEB J. 2014 Jul;28(7):2828-39.

Jacob D, Hunegnaw R, Sabyrzyanova TA, Pushkarsky T, Chekhov VO, Adzhubei AA, Kalebina TS, Bukrinsky M.
The ABCA1 domain responsible for interaction with HIV-1 Nef is conformational and not linear.
Biochem Biophys Res Commun. 2014 Jan31;444(1):19-23.

Cui HL, Guo B, Scicluna B, Coleman BM, Lawson VA, Ellett L, Meikle PJ, Bukrinsky M, Mukhamedova N, Sviridov D, Hill AF.
Prion infection impairs cholesterol metabolism in neuronal cells.
J Biol Chem. 2014 Jan10;289(2):789-802

Zhao RY, Bukrinsky MI.
HIV-1 accessory proteins: VpR.
Methods Mol Biol. 2014;1087:125-34

Top

2013

Iordanskiy S, Santos S, Bukrinsky M.
Nature, nurture and HIV: The effect of producer cell on viral physiology.
Virology. 2013 Sep 1;443(2):208-13. Review.

Rose H, Low H, Dewar E, Bukrinsky M, Hoy J, Dart A, Sviridov D.
The effect of HIV infection on atherosclerosis and lipoprotein metabolism: a one year prospective study.
Atherosclerosis. 2013 Jul;229(1):206-11.

Bukrinsky M, Orekhov A, Ditiatkovski M, Sviridov D.
Cyclophilins in atherosclerosis: a new therapeutic target?
Curr Pharm Des. 2013;19(33):5904-8. Review.

Top

2012

Tyagi M, Bukrinsky M.
Human immunodeficiency virus (HIV) latency: the major hurdle in HIV eradication.
Mol Med. 2012 Sep 25;18:1096-108.

Santos S, Obukhov Y, Nekhai S, Bukrinsky M, Iordanskiy S.
Virus-producing cells determine the host protein profiles of HIV-1 virion cores.
Retrovirology. 2012 Aug 13;9:65.

Cui HL, Grant A, Mukhamedova N, Pushkarsky T, Jennelle L, Dubrovsky L, Gaus K, Fitzgerald ML, Sviridov D, Bukrinsky M.
HIV-1 Nef mobilizes lipid rafts in macrophages through a pathway that competes with ABCA1-dependent cholesterol efflux.
J Lipid Res. 2012 Apr;53(4):696-708.

Dubrovsky L, Van Duyne R, Senina S, Guendel I, Pushkarsky T, Sviridov D, Kashanchi F, Bukrinsky M.
Liver X receptor agonist inhibits HIV-1 replication and prevents HIV-induced reduction of plasma HDL in humanized mouse model of HIV infection.
Biochem Biophys Res Commun. 2012 Mar 2;419(1):95-8.

Top

2011

Stemmy EJ, Balsley MA, Jurjus RA, Damsker JM, Bukrinsky MI, Constant SL.
Blocking cyclophilins in the chronic phase of asthma reduces the persistence of leukocytes and disease reactivation.
Am J Respir Cell Mol Biol. 2011 Nov;45(5):991-8.

Trachtenberg A, Pushkarsky T, Heine S, Constant S, Brichacek B, Bukrinsky M.
The level of CD147 expression correlates with cyclophilin-induced signaling and chemotaxis.
BMC Res Notes. 2011 Oct 11;4:396.

Levin A, Loyter A, Bukrinsky M.
Strategies to inhibit viral protein nuclear import: HIV-1 as a target.
Biochim Biophys Acta. 2011 Sep;1813(9):1646-53. Review.

Zhao RY, Li G, Bukrinsky MI.
Vpr-host interactions during HIV-1 viral life cycle.
J Neuroimmune Pharmacol. 2011 Jun;6(2):216-29. Review.

Heine SJ, Olive D, Gao JL, Murphy PM, Bukrinsky MI, Constant SL.
Cyclophilin A cooperates with MIP-2 to augment neutrophil migration.
J Inflamm Res. 2011;4:93-104

Top

2010

Balsley MA, Malesevic M, Stemmy EJ, Gigley J, Jurjus RA, Herzog D, Bukrinsky MI, Fischer G, Constant SL.
A cell-impermeable cyclosporine A derivative reduces pathology in a mouse model of allergic lung inflammation.
J Immunol. 2010 Dec15;185(12):7663-70.

Mujawar Z, Tamehiro N, Grant A, Sviridov D, Bukrinsky M, Fitzgerald ML.
Mutation of the ATP cassette binding transporter A1 (ABCA1) C-terminus disrupts HIV-1 Nef binding but does not block the Nef enhancement of ABCA1 protein degradation.
Biochemistry. 2010 Sep 28;49(38):8338-49.

Asztalos BF, Mujawar Z, Morrow MP, Grant A, Pushkarsky T, Wanke C, Shannon R, Geyer M, Kirchhoff F, Sviridov D, Fitzgerald ML, Bukrinsky M, Mansfield KG.
Circulating Nef induces dyslipidemia in simian immunodeficiency virus-infected macaques by suppressing cholesterol efflux.
J Infect Dis. 2010 Aug15;202(4):614-23

Morrow MP, Grant A, Mujawar Z, Dubrovsky L, Pushkarsky T, Kiselyeva Y, Jennelle L, Mukhamedova N, Remaley AT, Kashanchi F, Sviridov D, Bukrinsky M.
Stimulation of the liver X receptor pathway inhibits HIV-1 replication via induction of ATP-binding cassette transporter A1.
Mol Pharmacol. 2010 Aug;78(2):215-25.

Li G, Elder RT, Dubrovsky L, Liang D, Pushkarsky T, Chiu K, Fan T, Sire J, Bukrinsky M, Zhao RY.
HIV-1 replication through hHR23A-mediated interaction of Vpr with 26S proteasome.
PLoS One. 2010 Jun 29;5(6):e11371.

Yurchenko V, Constant S, Eisenmesser E, Bukrinsky M.
Cyclophilin-CD147 interactions: a new target for anti-inflammatory therapeutics.
Clin Exp Immunol. 2010 Jun;160(3):305-17. Review.

Weinstein RS, Weinstein MM, Alibek K, Bukrinsky MI, Brichacek B.
Significantly reduced CCR5-tropic HIV-1 replication in vitro in cells from subjects previously immunized with Vaccinia Virus.
BMC Immunol. 2010 May 18;11:23.

Crowe SM, Westhorpe CL, Mukhamedova N, Jaworowski A, Sviridov D, Bukrinsky M.
The macrophage: the intersection between HIV infection and atherosclerosis. J
Leukoc Biol. 2010 Apr;87(4):589-98. Review.

Malesević M, Kühling J, Erdmann F, Balsley MA, Bukrinsky MI, Constant SL, Fischer G.
A cyclosporin derivative discriminates between extracellular and intracellular cyclophilins.
Angew Chem Int Ed Engl. 2010;49(1):213-5.

Top

2009

Mukhamedova N, Rose H, Cui HL, Grant A, Tchoua U, Dart A, Bukrinsky M, Sviridov D.
Antiretroviral compounds and cholesterol efflux from macrophages.
Atherosclerosis. 2009 Oct;206(2):439-43.

Schlegel J, Redzic JS, Porter CC, Yurchenko V, Bukrinsky M, Labeikovsky W, Armstrong GS, Zhang F, Isern NG, DeGregori J, Hodges R, Eisenmesser EZ.
Solution characterization of the extracellular region of CD147 and its interaction with its enzyme ligand cyclophilin A.
J Mol Biol. 2009 Aug 21;391(3):518-35.

Li G, Bukrinsky M, Zhao RY.
HIV-1 viral protein R (Vpr) and its interactions with host cell.
Curr HIV Res. 2009 Mar;7(2):178-83. Review.

Abbadessa G, Accolla R, Aiuti F, Albini A, Aldovini A, Alfano M, Antonelli G, Bartholomew C, Bentwich Z, Bertazzoni U, Berzofsky JA, Biberfeld P, Boeri E, Buonaguro L, Buonaguro FM, Bukrinsky M, Burny A, Caruso A, Cassol S, Chandra P, Ceccherini-Nelli L, Chieco-Bianchi L, Clerici M, Colombini-Hatch S, de Giuli Morghen C, de Maria A, de Rossi A, Dierich M, Della-Favera R, Dolei A, Douek D, Erfle V, Felber B, Fiorentini S, Franchini G, Gershoni JM, Gotch F, Green P, Greene WC, Hall W, Haseltine W, Jacobson S, Kallings LO, Kalyanaraman VS, Katinger H, Khalili K, Klein G, Klein E, Klotman M, Klotman P, Kotler M, Kurth R, Lafeuillade A, La Placa M, Lewis J, Lillo F, Lisziewicz J, Lomonico A, Lopalco L, Lori F, Lusso P, Macchi B, Malim M, Margolis L, Markham PD, McClure M, Miller N, Mingari MC, Moretta L, Noonan D, O'Brien S, Okamoto T, Pal R, Palese P, Panet A, Pantaleo G, Pavlakis G, Pistello M, Plotkin S, Poli G, Pomerantz R, Radaelli A, Robertguroff M, Roederer M, Sarngadharan MG, Schols D, Secchiero P, Shearer G, Siccardi A, Stevenson M, Svoboda J, Tartaglia J, Torelli G, Tornesello ML, Tschachler E, Vaccarezza M, Vallbracht A, van Lunzen J, Varnier O, Vicenzi E, von Melchner H, Witz I, Zagury D, Zagury JF, Zauli G, Zipeto D.
Unsung hero Robert C. Gallo.
Science. 2009 Jan 9;323(5911):206-7.

Kadiu I, Wang T, Schlautman JD, Dubrovsky L, Ciborowski P, Bukrinsky M, Gendelman HE.
HIV-1 transforms the monocyte plasma membrane proteome.
Cell Immunol. 2009;258(1):44-58.

Damsker JM, Okwumabua I, Pushkarsky T, Arora K, Bukrinsky MI, Constant SL.
Targeting the chemotactic function of CD147 reduces collagen-induced arthritis.
Immunology. 2009 Jan;126(1):55-62.

Iordanskiy SN, Bukrinsky MI.
Analysis of viral and cellular proteins in HIV-1 reverse transcription complexes by co-immunoprecipitation.
Methods Mol Biol. 2009;485:121-34.

Top

2008

Mukhamedova N, Escher G, D'Souza W, Tchoua U, Grant A, Krozowski Z, Bukrinsky M, Sviridov D.
Enhancing apolipoprotein A-I-dependent cholesterol efflux elevates cholesterol export from macrophages in vivo.
J Lipid Res. 2008 Nov;49(11):2312-22.

Bukrinsky M.
How to engage Cofilin.
Retrovirology. 2008 Sep 22; 5:85.

Rose H, Hoy J, Woolley I, Tchoua U, Bukrinsky M, Dart A, Sviridov D.
HIV infection and high density lipoprotein metabolism.
Atherosclerosis. 2008 Jul;199(1):79-86.

Yurchenko V, Xue Z, Sherry B, Bukrinsky M.
Functional analysis of Leishmania major cyclophilin.
Int J Parasitol. 2008 May;38(6):633-9.

Wu W, Kehn-Hall K, Pedati C, Zweier L, Castro I, Klase Z, Dowd CS, Dubrovsky L, Bukrinsky M, Kashanchi F.
Drug 9AA reactivates p21/Waf1 and Inhibits HIV-1 progeny formation.
Virol J. 2008 Mar 18;5:41.

Top

2007

Pushkarsky T, Yurchenko V, Laborico A, Bukrinsky M.
CD147 stimulates HIV-1 infection in a signal-independent fashion.
Biochem Biophys Res Commun. 2007 Nov 23;363(3):495-9.

Damsker JM, Bukrinsky MI, Constant SL.
Preferential chemotaxis of activated human CD4+ T cells by extracellular cyclophilin A.
J Leukoc Biol. 2007 Sep;82(3):613-8.

Mukhamedova N, Fu Y, Bukrinsky M, Remaley AT, Sviridov D.
The role of different regions of ATP-binding cassette transporter A1 in cholesterol efflux.
Biochemistry. 2007 Aug 21;46(33):9388-98.

Liang D, Benko Z, Agbottah E, Bukrinsky M, Zhao RY.
Anti-vpr activities of heat shock protein 27.
Mol Med. 2007 May-Jun;13(5-6):229-39.

Benko Z, Liang D, Agbottah E, Hou J, Taricani L, Young PG, Bukrinsky M, Zhao RY.
Antagonistic interaction of HIV-1 Vpr with Hsf-mediated cellular heat shock response and Hsp16 in fission yeast (Schizosaccharomyces pombe).
Retrovirology. 2007 Mar 7;4:16.

Zhao RY, Elder RT, Bukrinsky M.
Interactions of HIV-1 viral protein R with host cell proteins.
Adv Pharmacol. 2007;55:233-60. Review.

Iordanskiy S, Bukrinsky M.
Reverse transcription complex: the key player of the early phase of HIV replication.
Future Virol. 2007 Jan 1;2(1):49-64.

Bukrinsky M, Sviridov D.
HIV and cardiovascular disease: contribution of HIV-infected macrophages to development of atherosclerosis.
PLoS Med. 2007 Jan;4(1):e43.

Top

2006

Bukrinsky M, Sviridov D.
Human immunodeficiency virus infection and macrophage cholesterol metabolism.
J Leukoc Biol. 2006 Nov;80(5):1044-51. Review.

Gwinn WM, Damsker JM, Falahati R, Okwumabua I, Kelly-Welch A, Keegan AD, Vanpouille C, Lee JJ, Dent LA, Leitenberg D, Bukrinsky MI, Constant SL.
Novel approach to inhibit asthma-mediated lung inflammation using anti-CD147 intervention.
J Immunol. 2006 Oct 1;177(7):4870-9.

Mujawar Z, Rose H, Morrow MP, Pushkarsky T, Dubrovsky L, Mukhamedova N, Fu Y, Dart A, Orenstein JM, Bobryshev YV, Bukrinsky M, Sviridov D.
Human immunodeficiency virus impairs reverse cholesterol transport from macrophages.
PLoS Biol. 2006 Oct;4(11):e365.

Brichacek B, Vanpouille C, Trachtenberg AJ, Pushkarsky T, Dubrovsky L, Martin G, Simon G, Bukrinsky M.
Long-term changes of serum chemokine levels in vaccinated military personnel.
BMC Immunol. 2006 Sep 11;7:21.

Bukrinsky M.
SNFing HIV transcription.
Retrovirology. 2006 Aug 9;3:49.

Yurchenko V, Constant S, Bukrinsky M.
Dealing with the family: CD147 interactions with cyclophilins.
Immunology. 2006 Mar;117(3):301-9. Review.

Iordanskiy S, Berro R, Altieri M, Kashanchi F, Bukrinsky M.
Intracytoplasmic maturation of the human immunodeficiency virus type 1 reverse transcription complexes determines their capacity to integrate into chromatin.
Retrovirology. 2006 Jan 12;3:4.

Top

2005

Li L, Li HS, Pauza CD, Bukrinsky M, Zhao RY.
Roles of HIV-1 auxiliary proteins in viral pathogenesis and host-pathogen interactions.
Cell Res. 2005 Nov-Dec;15(11-12):923-34. Review.

Haffar O, Dubrovsky L, Lowe R, Berro R, Kashanchi F, Godden J, Vanpouille C, Bajorath J, Bukrinsky M.
Oxadiazols: a new class of rationally designed anti-human immunodeficiency virus compounds targeting the nuclear localization signal of the viral matrix protein.
J Virol. 2005 Oct;79(20):13028-36.

Pushkarsky T, Yurchenko V, Vanpouille C, Brichacek B, Vaisman I, Hatakeyama S, Nakayama KI, Sherry B, Bukrinsky MI.
Cell surface expression of CD147/EMMPRIN is regulated by cyclophilin 60.
J Biol Chem. 2005 Jul 29;280(30):27866-71.

Arora K, Gwinn WM, Bower MA, Watson A, Okwumabua I, MacDonald HR, Bukrinsky MI, Constant SL.
Extracellular cyclophilins contribute to the regulation of inflammatory responses.
J Immunol. 2005 Jul 1;175(1):517-22.

Yurchenko V, Pushkarsky T, Li JH, Dai WW, Sherry B, Bukrinsky M.
Regulation of CD147 cell surface expression: involvement of the proline residue in the CD147 transmembrane domain.
J Biol Chem. 2005 Apr 29;280(17):17013-9.

Zhao RY, Bukrinsky M, Elder RT.
HIV-1 viral protein R (Vpr) & host cellular responses.
Indian J Med Res. 2005 Apr;121(4):270-86. Review.

Haffar O, Bukrinsky M.
Nuclear translocation as a novel target for anti-HIV drugs.
Expert Rev Anti Infect Ther. 2005 Feb;3(1):41-50. Review.

Top

2004

Benko Z, Liang D, Agbottah E, Hou J, Chiu K, Yu M, Innis S, Reed P, Kabat W, Elder RT, Di Marzio P, Taricani L, Ratner L, Young PG, Bukrinsky M, Zhao RY.
Anti-Vpr activity of a yeast chaperone protein.
J Virol. 2004 Oct;78(20):11016-29.

Iordanskiy S, Zhao Y, DiMarzio P, Agostini I, Dubrovsky L, Bukrinsky M.
Heat-shock protein 70 exerts opposing effects on Vpr-dependent and Vpr-independent HIV-1 replication in macrophages.
Blood. 2004 Sep15;104(6):1867-72.

Iordanskiy S, Zhao Y, Dubrovsky L, Iordanskaya T, Chen M, Liang D, Bukrinsky M.
Heat shock protein 70 protects cells from cell cycle arrest and apoptosis induced by human immunodeficiency virus type 1 viral protein R.
J Virol. 2004 Sep;78(18):9697-704.

Bukrinsky M, Zhao Y.
Heat-shock proteins reverse the G2 arrest caused by HIV-1 viral protein R.
DNA Cell Biol. 2004 Apr;23(4):223-5.

Bukrinsky M.
A hard way to the nucleus.
Mol Med. 2004 Jan-Jun;10(1-6):1-5. Review.

Top

2003

Marzio PD, Sherry B, Thomas EK, Franchin G, Schmidtmayerova H, Bukrinsky M.
beta-Chemokine production in CD40L-stimulated monocyte-derived macrophages requires activation of MAPK signaling pathways.
Cytokine. 2003 Aug 7;23(3):53-63.

Top

2002

Al-Abed Y, Dubrovsky L, Ruzsicska B, Seepersaud M, Bukrinsky M.
Inhibition of HIV-1 nuclear import via schiff base formation with arylene bis(methylketone) compounds.
Bioorg Med Chem Lett. 2002 Nov 4;12(21):3117-9.

Brichacek B, Bukrinsky M.
Highly active antiretroviral therapy and beta-chemokines.
Clin Exp Immunol. 2002 Nov;130(2):169-71.

Twu C, Liu NQ, Popik W, Bukrinsky M, Sayre J, Roberts J, Rania S, Bramhandam V, Roos KP, MacLellan WR, Fiala M.
Cardiomyocytes undergo apoptosis in human immunodeficiency virus cardiomyopathy through mitochondrion- and death receptor-controlled pathways.
Proc Natl Acad Sci U S A. 2002 Oct 29;99(22):14386-91.

Iordanskiy S, Iordanskaya T, Quivy V, Van Lint C, Bukrinsky M.
B-oligomer of pertussis toxin inhibits HIV-1 LTR-driven transcription through suppression of NF-kappaB p65 subunit activity.
Virology. 2002 Oct 10;302(1):195-206.

Liu NQ, Lossinsky AS, Popik W, Li X, Gujuluva C, Kriederman B, Roberts J, Pushkarsky T, Bukrinsky M, Witte M, Weinand M, Fiala M.
Human immunodeficiency virus type 1 enters brain microvascular endothelia by macropinocytosis dependent on lipid rafts and the mitogen-activated protein kinase signaling pathway.
J Virol. 2002 Jul;76(13):6689-700.

Bukrinsky MI.
Cyclophilins: unexpected messengers in intercellular communications.
Trends Immunol. 2002 Jul;23(7):323-5. Review.

Yurchenko V, Zybarth G, O'Connor M, Dai WW, Franchin G, Hao T, Guo H, Hung HC, Toole B, Gallay P, Sherry B, Bukrinsky M.
Active site residues of cyclophilin A are crucial for its signaling activity via CD147.
J Biol Chem. 2002 Jun 21;277(25):22959-65

Agostini I, Popov S, Hao T, Li JH, Dubrovsky L, Chaika O, Chaika N, Lewis R, Bukrinsky M.
Phosphorylation of Vpr regulates HIV type 1 nuclear import and macrophage infection.
AIDS Res Hum Retroviruses. 2002 Mar 1;18(4):283-8.

Top

2001

Yurchenko V, O'Connor M, Dai WW, Guo H, Toole B, Sherry B, Bukrinsky M.
CD147 is a signaling receptor for cyclophilin B.
Biochem Biophys Res Commun. 2001 Nov9;288(4):786-8.

Pushkarsky T, Zybarth G, Dubrovsky L, Yurchenko V, Tang H, Guo H, Toole B, Sherry B, Bukrinsky M.
CD147 facilitates HIV-1 infection by interacting with virus-associated cyclophilin A.
Proc Natl Acad Sci U S A. 2001 May22;98(11):6360-5.

Gujuluva C, Burns AR, Pushkarsky T, Popik W, Berger O, Bukrinsky M, Graves MC, Fiala M.
HIV-1 penetrates coronary artery endothelial cells by transcytosis.
Mol Med. 2001 Mar;7(3):169-76.

Alfano M, Vallanti G, Biswas P, Bovolenta C, Vicenzi E, Mantelli B, Pushkarsky T, Rappuoli R, Lazzarin A, Bukrinsky M, Poli G.
The binding subunit of pertussis toxin inhibits HIV replication in human macrophages and virus expression in chronically infected promonocytic U1 cells.
J Immunol. 2001 Feb1;166(3):1863-70.

Fiala M, Gujuluva C, Berger O, Bukrinsky M, Kim KS, Graves MC.
Chemokine receptors on brain endothelia--keys to HIV-1 neuroinvasion?
Adv Exp Med Biol. 2001;493:35-40. Review.

Pushkarsky T, Dubrovsky L, Bukrinsky M.
Lipopolysaccharide stimulates HIV-1 entry and degradation in human macrophages.
J Endotoxin Res. 2001;7(4):271-6.

Top

2000

Agostini I, Popov S, Li J, Dubrovsky L, Hao T, Bukrinsky M.
Heat-shock protein 70 can replace viral protein R of HIV-1 during nuclear import of the viral preintegration complex.
Exp Cell Res. 2000 Sep 15;259(2):398-403.

Alfano M, Pushkarsky T, Poli G, Bukrinsky M.
The B-oligomer of pertussis toxin inhibits human immunodeficiency virus type 1 replication at multiple stages.
J Virol. 2000 Sep;74(18):8767-70.

Glushakova S, Dubrovsky L, Grivel J, Haffar O, Bukrinsky M.
Small molecule inhibitor of HIV-1 nuclear import suppresses HIV-1 replication in human lymphoid  tissue ex vivo: a potential addition to current anti-HIV drug repertoire.
Antiviral Res. 2000 Aug;47(2):89-95.

Haffar OK, Popov S, Dubrovsky L, Agostini I, Tang H, Pushkarsky T, Nadler SG, Bukrinsky M.
Two nuclear localization signals in the HIV-1 matrix protein regulate nuclear import of the HIV-1 pre-integration complex.
J Mol Biol. 2000 Jun 2;299(2):359-68.

Sherry B, Schmidtmayerova H, Zybarth G, Dubrovsky L, Raabe T, Bukrinsky M.
Nitric oxide regulates MIP-1alpha expression in primary macrophages and T lymphocytes: implications for anti-HIV-1 response.
Mol Med. 2000 Jun;6(6):542-9.

Franchin G, Zybarth G, Dai WW, Dubrovsky L, Reiling N, Schmidtmayerova H, Bukrinsky M, Sherry B.
Lipopolysaccharide inhibits HIV-1 infection of monocyte- derived macrophages through direct and sustained down-regulation of CC chemokine receptor 5.
J Immunol. 2000 Mar 1;164(5):2592-601.

Top